Professor Tuncay Delibasi - Department of Endocrinology

Leptin is a peptide hormone that secrets from fat cells of the human body. It helps to regulate body mass, food intake and reproductive functions. It plays an important role in fetal growth, angiogenesis, proinflammatory immune responses and lipolysis. It is a product of the Ob-gene (obese gene). The name leptin is derived from a Greek word – “leptos” which means thin. It acts as a fat controller in the human body. What causes leptin resistance? Leptin resistance causes unwanted obesity in human bodies. The main reasons for leptin resistance are: Increasing total body mass Reduced satiety Overconsumption of nutrients These factors often lead to obesity. It reduces the efficiency of exogenous leptin usage as a therapeutic agent. Therefore, the combination of leptin therapy and leptin sensitizers helps overcome resistance and then obesity. Tuncay Delibasi –  a renowned Turkish professor of the endocrinology department is a famous name who is working on advanced level resea...